- Nelson Mandela, former President, Nobel Peace Prize Winner 1993
- Desmond Tutu, General Secretary of the South African Council of Churches, Nobel Peace Prize Winner 1984
- Walter Sisulu
- Steve Biko, anti-apartheid activist
- Hector Pieterson, came to represent the anger and tragedy of a day that changed the course of South African history, sparking months of clashes between police, schoolchildren and protesters
- Nadine Gordimer, recipient of the 1991 Nobel Prize in Literature
- FW de Klerk - Nobel Peace Prize Winner with Nelson Mandela, 1993
- Navanethem Pillay, UN High Commissioner for Human Rights
- Judge Richard Goldstone, former Chief Prosecutor of the United Nations International Criminal Tribunals for the former Yugoslavia and Rwanda
- Dr. Liam Pedersen, former NASA robotics researcher who was instrumental in creating the Mars rover as part of his work on future planetary exploration
- Elon Musk, CEO and product architect of Tesla Motors and the CEO/CTO of Space Exploration Technologies (SpaceX)
- Dr. Mankekolo Mahlangu-Ngcobo, Consultant for The Johns Hopkins Health Systems-Community Outreach. She was a consultant with the US Public Health Service, Maternal and Child Health Bureau and conducted evaluation of a Healthy Start Program in Boston. Dr. Mahlangu-Ngcobo is an ordained minister in the African Methodist Episcopal Church (AMEC) and an author of nine books.
- Penelope Andrews - lawyer
- Miriam Makeba, singer known as Mama Africa and the Empress of African song
- Lucky Dube, alongside Bob Marley, was one of the great reggae artists, singing about social problems
- Hugh Masekela, South African trumpeter, flugelhornist, cornetist, composer, and singer
- Charlize Theron, The Charlize Theron Africa Outreach Project (CTAOP) invests in African youth to keep themselves safe from HIV/AIDS. CTAOP was created in 2007 by the Academy Award winning actress and UN Messenger of Peace, with the hope of making a difference in fighting HIV in South Africa. Although the geographic scope of CTAOP is Sub-Saharan Africa, South Africa has remained the primary area of focus.
- Arnold Vosloo, Actor
- Stelio Savante, Actor
- Siyabulela Xuza, Scientist
- David Tlale, Fashion Designer
- Ladysmith Black Mambazo, Grammy Award Winning Choir
- Soweto Gospel Choir
- Lebo M - South African singer and songwriter
- Tsidii Le Loka - Vocalist, Actor, Composer, Speaker
- Mpho Gift Ngoepe, Major League Baseball infielder
- Bruce Fordyce, Marathoner- Originally published in UltraRunning Magazine, May/June 2012, and reproduced with permission.
- Alf Kumalo, one of South Africa’s leading documentary photographers
- João Silva, one of documentary photographers who covered the violent birth pangs of the democratic South Africa
- Greg Marinovich, Pulitzer Prize-winning photographer doing conflict, documentary and news photography around the globe.
- Agnes Matlebjane - Author, Footsteps- My Life As An Au Pair, (also available at XLibris), Exchange Student at Kean University
- Warren Adams, Ballet dancer and choreographer
- Born in the RSA - and big in the USA